Long non-coding RNA KCNQ10T1/miR-19a-3p/SMAD5 axis promotes osteogenic differentiation of mouse bone mesenchymal stem cells

Abstract Background Bone fracture is a common orthopedic disease that needs over 3 months to recover.Promoting the osteogenic differentiation of bone mesenchymal stem cells (BMSCs) is beneficial for fracture healing.Therefore, this research aimed to study the roles of long non-coding RNA (lncRNA) KCNQ10T1 in osteogenic differentiation of BMSCs.Meth

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Estimating the time of Highly Pathogenic Avian Influenza virus introduction into United States poultry flocks during the 2022/24 epizootic.

Following confirmation of the first case of the ongoing U.S.HPAI H5N1 epizootic in commercial poultry on February 8, 2022, the virus has continued to devastate the U.S.poultry sector and the pathogen has since managed to cross over to livestock and a few human cases have also been reported.Efficient outbreak management benefits greatly from timely

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